Generic Propecia: Taking Details, Doses, Drug interactions

Propecia is a pharmaceutical agent that is specifically designed to combat hair loss and promote hair regrowth in male patients. This medication is formulated to address alopecia, which is a condition characterized by male pattern baldness or androgenetic alopecia caused by the conversion of male hormones. Due to its targeted mechanism of action, Propecia is not indicated for use in female patients. The minimal duration of treatment is six months, which is necessary to achieve optimal results. This underscores the need for patients to follow the prescribed course of therapy to maximize the benefits of this medication.

Propecia in its current form came to being in 1997, when finasteride, previously used as benign prostate hyperplasia (BPH) drug, received FDA approval for male pattern baldness treatment.

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Results

Does Propecia really work? Propecia reviews based on clinical studies demonstrate that finasteride 1 mg daily decreases continued hair loss and increases hair growth in males with androgenetic alopecia. To improve hair growth must be finasteride use for a long time. After treatment for a year or more, the increase hair growth on the order of 7-10% more hairs than at baseline.

The medical profile of Propecia before and after moments indicates the treatment also provides greater increase in hair thickness and length. Side effects like decreased libido, erectile difficulty, ejaculation and depression may occur in fewer than 1 in 100 people have been mentioned in studies. General Propecia success rate can be estimated at 30%.

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How does it works?

Finasteride is a substance contained in Propecia hair loss drug. This preparation is only for men when the substance may cause severe damage to the fetus in pregnant women.

Propecia works by inhibiting the enzyme 5-alpha reductase, preventing testosterone form conversion to dehydrotestosterone, or DHT. DHT is the substance that causes male pattern baldness, and to some extent also female pattern hair loss – that is, genetic hair loss. It is the individual sensitivity to the enzyme that determines how strongly the hair loss will be. At genetic hair loss the growth of new hairs is inhibited whilst the existing shrink and eventually disappear. By reducing the sensitivity to the enzyme and thus the formation of DHT finasteride slows this process and allows new hair to regrow.

How is Propecia taken?

In MPB, 1 tablet of Propecia (finasterid 1 mg) is taken daily with or without meals. There is no evidence that an increased dose results in increased effect. Efficacy and duration of treatment should continuously be assessed by the treating physician. It generally takes three to six months of daily treatment, before signs of stabilization of hair loss can be expected. Continued treatment is recommended to maintain the effect. Discontinuation of treatment will lead to the positive effects which begins within 6 months and returns to baseline by months 9 to 12.

Doses information

Propecia dose of finasteride is 1 mg, as opposed to Proscar that contains finasteride 5 mg. Propecia for hair loss is taken at the dose of 1 mg on daily basis during the minimally effective period of time (at least 6 months).

What you should know before taking

As far as Propecia prescription is concerned, the drug is appointed to individuals with no contradictory comorbidity conditions and those without known allergies towards the drug and its components. Check for the list of Propecia contraindications below on this page (this might not be full) and manufacturer’s instruction found in the original drug package.

Contraindications

According to the manufacturer that refers to several decades of clinical studies, Propecia has no known contraindications apart from gender. Finasteride is absolutely not intended for use in women because of dangers it may pose in terms of hormonal disruption and / or damage to fetus and suckings in pregnant / breastfeeding women, respectively.

This begs the questions, is Propecia safe for every patient category? The answer is yes, with minor reservations made for the cases of individual intolerance and allergies towards the drug or its components. It is a good idea to discuss your concerns with prescriber before taking drugs containing finasteride.

Drug interactions

No interactions of Propecia have been identified in the course of clinical studies. Although the risk for finasteride to affect the kinetics of other drugs is considered small, it is probable that inhibitors and inducers of cytochrome P450 3A4 (propranolol, digoxin, glyburide, warfarin, theophylline and phenazone) may influence the plasma concentration of finasteride. Based on established safety margins, an increase in the plasma concentration due to concomitant use of such inhibitors is probably not of clinical significance. The effects of simultaneous use of cytochrome P450 3A4 inhibitors and finasteride has been tested in humans and no clinically significant interactions have been found.

Important information

Propecia contains lactose monohydrate as a filler. This information should be taken into consideration by individuals suffering from lactose intolerance. If your prescriber considers the benefits of the drug’s use prevailing over potential risks, continue with the therapy under a doctor’s guidance and monitor your bodily reactions closely and regularly.

Side effects

Propecia as such has practically no side effects, but there is one adverse event that is commonly attributed to the use of finasteride containing pharmaceuticals, and it is erectile dysfunction (ED, impotence). A significant drop in libido is also observed in reports of patients in the later stages of Propecia therapy course. It is not, however, clinically proven that side effects of Propecia include ED or diminished libido. In patients taking Propecia erectile dysfunction is statistically higher in occurrence as patients advance into their treatment course, but the symptoms are also reported to disappear as the course continues.

Crushed or broken tablets should not be handled by women who are or may become pregnant, because of possible absorption of finasteride with consequent potential risk to a male fetus. The tablets are film-coated to prevent contact with the active ingredient during normal handling, provided that they are not broken or crushed.

Other side effects of Propecia are as follows:

• hypersensitivity reactions such as rash, pruritus, urticaria and angioedema (including swelling of the lips, tongue, throat, and face).
• elevated liver enzymes
• erectile dysfunction, ejaculation disorder (including decreased volume of ejaculate)
• breast tenderness and enlargement, Testicular pain, infertility
• palpitations

Storage information

Propecia tablets should not be stored in temperatures above 86° F (30° C). Storage conditions of Propecia presuppose isolation from humidity and heat sources, as well as impermeability for sun rays. Keep the drugs out of the reach of minors and in places unavailable for pets. Do not use after best before date.