Erythromycin (Sulfisoxazole) – A Macrolide Antibiotic to Prevent Infections

Erythromycin, a macrolide antibiotic, offers a broad spectrum of applications in clinical practice. This potent antimicrobial agent effectively targets a range of bacterial pathogens, including those responsible for pneumonia, strep throat, and other respiratory infections. Beyond infectious diseases, erythromycin is also commonly used to treat acne, stomach ulcers, and select sexually transmitted infections.

One of the key advantages of erythromycin is its favorable safety profile. This antibiotic is generally well-tolerated, with few adverse effects reported. Furthermore, it remains an effective treatment option for infections that may be resistant to other antibiotics. Notably, erythromycin is a viable treatment option for certain populations, including pregnant women and children who may not be candidates for other antibiotic therapies.

Despite its benefits, erythromycin is not without limitations. It has the potential to interact with other medications, such as antacids, certain heart medications, and cholesterol-lowering drugs, which can lead to serious side effects. In addition, erythromycin is known to cause gastrointestinal symptoms, such as nausea, vomiting, and diarrhea, which can negatively impact patient tolerability and adherence to treatment.

Cost of Generic and Brand

Also available as a branded macrolide antibiotic drug Eryc Delayed Release Capsule 333mg, generic Erythromycin comes in the form of oral tablets of 250mg and 500mg. The average retail cost of 100 capsules of the branded drug is $132, while the same quantity of generic Erythromycin 250mg from Advance Canadian Pharmacy will be priced at $70.

Erythromycin (brand)

  • Eryc Delayed Release Capsule 333mg: available in the quantity of 100 capsules, branded Eryc (Erythromycin) 333mg manufactured in Canada will cost $131.99 per package or $1.32 per unit.

Erythromycin (generic drug)

  • Erythromycin 250mg: available in the quantity of 100 tablets, generic Erythromycin 250mg manufactured in Canada will cost $69.99 per package or $0.70 per unit.
  • Erythromycin 500mg: available in the quantity of 100 tablets, generic Erythromycin 500mg manufactured in Canada will cost $99.99 per package or $1.00 per unit.

The Pros and Cons

Erythromycin is often used to treat respiratory tract infections, sexually transmitted diseases, and skin infections. However, erythromycin can also have some side effects. Here are some pros and cons of erythromycin to consider before starting treatment:


  • Erythromycin is generally effective against the bacteria it is meant to target.
  • It is available in both oral and topical forms.
  • It is relatively affordable.


  • Erythromycin can cause stomach upset, dyspepsia, and vomiting.
  • It can also cause diarrhea.
  • In rare cases, erythromycin can cause serious allergic reactions.

Is Erythromycin Right for You?

There are a number of reasons you may be considering erythromycin. It may be that you have an infection that is resistant to other antibiotics, or you may just want a more natural alternative. Whatever the reason, it’s important to make sure that erythromycin is the right choice for you.

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There are a few things to consider when deciding whether or not erythromycin is right for you. First, you need to make sure that the infection you have is actually susceptible to this antibiotic. Second, you should weigh the risks and benefits of using erythromycin versus another antibiotic option. Finally, you should discuss your decision with your doctor to make sure it’s the right choice for your specific situation.

If you’ve decided that erythromycin is the right choice for you, there are some things you can do to make sure you get the most out of this antibiotic.

  • First, take the entire course of treatment despite the fact that you might feel better early on.
  • Second, avoid taking any other antibiotics while taking erythromycin unless your doctor specifically tells you to do so.
  • Finally, remember that while erythromycin can be effective in treating certain infections, it doesn’t work for everyone and may not be as effective as other antibiotics.

The Risks of Erythromycin

Erythromycin is an antibiotic that is commonly used to treat bacterial infections. While it is generally considered to be safe, there are some potential risks associated with its use.

One of the most common adverse effects is gastrointestinal upset, which can include nausea, vomiting, and diarrhea. This side effect is usually mild and goes away on its own within a few days. However, erythromycin can also cause more severe gastrointestinal problems, such as inflammation of the stomach lining (gastritis) and intestinal ulcers. These more serious side effects are rare, but can be very painful and may require hospitalization.

Erythromycin can also cause allergies among some individuals. The most common signs being hives, rash, difficulty breathing, etc. These reactions are usually not life-threatening but can be very uncomfortable. If you experience any of these symptoms after taking erythromycin, you should see a doctor right away.

Finally, erythromycin can interact with other medications that you may be taking. It is important to tell your doctor about all of the meds you’re taking. Certain medications can increase the risk of side effects when taken with erythromycin, so it is important to be aware of these interactions before starting treatment.

The Bottom Line

Erythromycin is an antibiotic that is commonly prescribed for a variety of infections. It is often used as a first-line treatment for strep throat, but can also be used for other conditions such as pneumonia, Lyme disease, and Rocky Mountain spotted fever.

Erythromycin is typically well-tolerated by most patients, although some adverse effects may occur. In some cases, more severe side effects may occur, including dizziness and having difficulty breathing.

Overall, erythromycin appears to be a safe and effective antibiotic when used appropriately. However, it is important to weigh the risks and benefits before starting treatment.

Frequently Asked Questions

Erythromycin is a commonly used antibiotic that is often prescribed to treat bacterial infections. It is usually taken orally, either as a pill or in liquid form, but can also be administered intravenously.

There are many questions and misconceptions about erythromycin that people may have. Here are the most common ones:

Can I take erythromycin if I am allergic to penicillin?

Yes, erythromycin is not related to penicillin and therefore does not cause an allergic reaction. However, some people who are allergic to penicillin may still experience a reaction from erythromycin. If this happens, you should consult your doctor before taking it.

Can I take erythromycin if I am pregnant?

It is best to avoid taking erythromycin during pregnancy unless your doctor recommends otherwise.

Can I take erythromycin with other medications?

Yes, erythromycin can be taken with other medications without any problems.

How long does it take for erythromycin to work?

Erythromycin works best when taken at the first signs of infection. It usually takes between 12 and 24 hours for symptoms to start improving after starting treatment with erythromycin. 5-10 days of treatment is usually enough for recovery from most infections.

Consumer information and Disclaimer

The information we provide on this page is not intended to substitute a physical examination and a consultation in your doctor’s office followed with the prescription of the best-suited medicating. Furthermore, this information may appear incomplete, partial, non-specific and otherwise unfitted to be used as the recommendation basis for any type of treatment. We try to create scientifically accurate copies that go through multiple checkpoints and are curated by professionals, but we reserve the right for occasional errors. Seek doctor’s advice before commencing, renewing or discontinuing any drug. The same concerns recommendations and best practices for drug application, effects, caution and adverse reactions.